自从发现IgE抗体就是速发型过敏反应性疾病的介导物质以后,对这种抗体的生理、生化性质进行了大量的研究。特别是最近几年来有关IgE抗体应答调节的研究进展迅速,从而为最终解决由IgE抗体介导的过敏性疾病的治疗问题提供了必不可少的知识。本文拟就变应原的性质,IgE抗体应答中独特型网络的调节,T-B细胞的相互作用,以及可溶性因子参 Since the discovery that IgE antibodies are mediators of immediate-onset hypersensitivity diseases, a great deal of research has been conducted on the physiological and biochemical properties of this antibody. Especially, the research on the regulation of IgE antibody response is rapid in recent years, which provides the essential knowledge for finally solving the treatment problem of allergic diseases mediated by IgE antibody. In this paper, the nature of the allergen, IgE antibody response unique network regulation, T-B cell interactions, as well as soluble factor