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目的观察益生菌治疗肝硬化自发性细菌性腹膜炎(SBP)患者的效果。方法将60例肝硬化自发性细菌性腹膜炎随机分成2组,对照组30例,予抗感染、保肝、降门脉高压、利尿、营养支持治疗;治疗组30例,在对照组的综合治疗基础上加用地衣芽胞杆菌胶囊,每日3次,每次2粒,连服21 d后观察感染控制及肝功能变化情况。结果治疗组总有效率明显高于对照组,除了腹痛、腹部压痛无差异外,发热、腹泻消失、腹水常规、肝功能改善方面与对照组比较差异存在统计学意义(P<0.05)。结论益生菌对肝硬化并发自发性腹膜炎有一定治疗效果。
Objective To observe the effect of probiotics on patients with spontaneous bacterial peritonitis (SBP) due to cirrhosis. Methods Sixty patients with cirrhosis spontaneous bacterial peritonitis were randomly divided into two groups, the control group of 30 cases, to anti-infection, hepatoprotective, portal hypertension, diuretic, nutritional support treatment; treatment group of 30 patients in the control group of comprehensive treatment Based on the addition of Bacillus licheniformis capsules, 3 times a day, each 2 capsules, even for 21 days after infection control and changes in liver function observed. Results The total effective rate of the treatment group was significantly higher than that of the control group. There was no significant difference between the treatment group and the control group except for the abdominal pain and abdominal tenderness, fever, diarrhea disappeared, ascites routine and liver function improvement (P <0.05). Conclusion Probiotics have some therapeutic effects on cirrhosis and spontaneous peritonitis.