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目的探讨创伤性脂肪栓塞综合征(FES)早期诊断的先兆征象和继发性栓塞于心、肝、肾的临床特征。方法回顾性分析34例 FES 的临床表现,结合文献资料分析研究各种检查阳性结果的临床意义。结果 D-二聚体升高,血色素或红细胞压积进行性降低,血纤维蛋白原升高为 FES 诊断中最敏感的指标,分别为80%、79.4%、76.5%。继发性栓塞于心、肝、肾血清酶学、蛋白尿阳性率依次为89.5%和58%。结论 FES 是存在有多器官损害的一组症候群。检查凝血因子、肺部 CT、脑部 MRI,能早期明确诊断
Objective To investigate the signs of early diagnosis of traumatic fat embolism syndrome (FES) and the clinical features of secondary embolism in heart, liver and kidney. Methods Retrospective analysis of 34 cases of FES clinical manifestations, combined with the literature analysis of the clinical significance of various positive results. Results D-dimer increased hemoglobin or hematocrit decreased, fibrinogen increased to the most sensitive diagnostic FES indicators were 80%, 79.4%, 76.5%. Secondary embolism in heart, liver and kidney serum enzyme, proteinuria positive rates were 89.5% and 58%. Conclusion FES is a group of multiple organ damage syndromes. Check coagulation factors, lung CT, brain MRI, early diagnosis can be clear