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龋病是危害人类口腔健康最常见的疾病,是口腔致龋菌群、宿主、食物及时间多因素综合作用的疾病。据WHO相关研究显示,随着口腔医学的发展,在世界范围内龋失补指数(DMFT)有所下降,但是仍然影响着60~90的学龄儿童和大部分的成年人的身体和生活质量[1]。利用碳水化合物发酵产生乳酸是致龋菌的重要特征,是龋病发生的直接原因。多数口腔细菌可通过代谢碳水化合物产生有机酸,随着代谢酸性产物
Caries is the most common disease that endangers the oral health of human beings. It is a disease that combines the cariogenic oral flora, host, food and time with many factors. According to WHO-related studies, with the development of stomatology, there has been a decrease in DMFT worldwide, but still affects the body and quality of life of 60 to 90 school-age children and most adults [ 1]. The use of carbohydrate fermentation to produce lactic acid is an important feature of cariogenic bacteria, is the direct cause of dental caries. Most oral bacteria can produce organic acids by metabolizing carbohydrates, with the metabolic acid product