用透射电镜进一步观察了湖北钉螺脑神经节的纤维鞘、神经节胞体区和神经纤维网的超微结构，并且在神经纤维网部位首次发现了两个典型突触。经氯硝柳胺浸泡后，钉螺脑神经节的超微结构发生改变，神经纤维、神经胶质细胞和神经细胞内的线粒体由变性至坏死，神经细胞体内的糖原含量显著减少，神经纤维网也发生变性坏死，这为阐明氯硝柳胺的灭螺机制提供了有用的资料。 Transmission electron microscopy was used to further observe the ultrastructure of fibrous sheath, gangliosomal region and nerve fiber network in the brain of Neurocarotus japonicus, and two typical synapses were found in the area of ​​neural network. After immersion with niclosamide, the ultrastructure of the brain of the snail brain changed. The mitochondria in the nerve fibers, glial cells and nerve cells changed from degeneration to necrosis, and the content of glycogen in nerve cells was significantly reduced. The nerve fiber network Also degeneration and necrosis, which provide useful information for clarifying the mechanism of snail control of niclosamide.