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利用光镜,电镜及体视学方法对人类绝经后不同时期的乏常子宫内膜腺上皮进行形态学观察及定量分析。三组标本共21例分别取自绝经后5年内,6~9年,10年以上的妇女,结果发现绝经后时间愈长,腺体的体密度愈大,而腺细胞及腺细胞核的体密度却无明显差异。腺上皮分泌细胞的徽绒毛,胞突,线粒体,粗面内质网的数量均较少,滑面内质网,高尔基氏器不发达且少见。游离核糖体,糖原,脂滴少见。退化的分泌细胞缩小且常有线粒体及粗面内质网肿胀。纤毛细胞极少见。各组均可见亮细胞。基底膜均质,连续。说明人类绝经后子宫内膜腺上皮形态结构的老化改变是一种量变的过程。
Morphological observation and quantitative analysis of the abnormal endometrial glandular epithelium in different stages of postmenopausal period were conducted by light microscope, electron microscope and stereology. Twenty-one specimens of three groups were taken from women within 5 years after menopause, from 6 to 9 years and over 10 years respectively. The results showed that the longer the time after menopause, the greater the body density of the gland, while the body density of glandular cells and glandular nuclei No significant difference. Glandular epithelial cells secreting fluff, cell processes, mitochondria, the number of rough endoplasmic reticulum are less, smooth endoplasmic reticulum, Gallstone is not developed and rare. Free ribosomes, glycogen, lipid droplets rare. Degenerate secretory cells shrink and often have mitochondria and rough endoplasmic reticulum swelling. Cilia cells are rare. Bright cells were seen in all groups. Basement membrane homogeneous, continuous. That human endometrial glandular epithelial morphology after menopause aging change is a quantitative process.