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本文研究了含乙醇、三乙醇胺、pH7.2磷酸缓冲液的水溶液系统中,0.5%月桂氮酮可使消炎痛溶液的体外透皮吸收增加3倍,且0.5%~10%的浓度促进消炎痛吸收的作用几无区别(P>0.05)。
In this paper, 0.5% Azone was used to increase the transdermal absorption of indomethacin solution in vitro by 3 times and the concentration of 0.5% ~ 10% to indomethacin in an aqueous solution containing ethanol, triethanolamine and pH 7.2 phosphate buffer Absorption effect of several no difference (P> 0.05).