组胺H_2受体阻断剂70年代后期H_2受体阻断剂(以甲氰咪胍为代表)问世以来,消化性溃疡的治疗上发生了一次革命,随后第2代雷尼替丁,第3代法莫替丁及罗沙替丁、尼沙替丁等也相继出现。H_2受体阻断剂对消化性溃疡的疗效已得到肯定。第2代、第3代等药物的区别,在于药物的剂量及副反应较少,服用更方便。罗沙替丁的作用是雷尼替丁的2 Histamine H 2 Receptor Blocker Since the advent of the H 2 receptor blocker (represented by cimetidine) in the late 1970s, a revolution occurred in the treatment of peptic ulcer, followed by the second generation of ranitidine, 3 generations of famotidine and roxatiding, nisatin for one after another also appeared. H 2 receptor blockers efficacy of peptic ulcer has been affirmed. The second generation, third generation and other drugs the difference lies in the dose of the drug and fewer side effects, taking more convenient. The effect of roxatidine is 2 for ranitidine