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从石杉科植物蛇足石杉中分离出三个生物碱(Ⅰ～Ⅲ)。经光谱数据和衍生物的制备证明:生物碱(Ⅰ)和(Ⅲ)分别为石杉碱乙(Ⅰ)和N-甲基石杉碱乙(Ⅲ);生物碱(Ⅱ)为新化合物,命名为蛇足石杉碱(huperzinine)。本文报告碱(Ⅱ)的结构测定。(Ⅱ)的生物活性正在研究中。
Three alkaloids (I-III) were isolated from Huperzia serrata. The spectral data and the preparation of derivatives proved that the alkaloids (I) and (III) are huperzine B (I) and N-methylhuperzine B (III), respectively; alkaloids (II) are new compounds. Named Huperzinine. This article reports the structural determination of base (II). The biological activity of (II) is under study.