淡色库蚊经溴氰菊酯选育１０代，Ｌｅ５０由０．０４０２ｐｐｍ上升至２１．２７３８ｐｐｍ，抗性高达５２９．２０倍，抗性呈指数曲线上升；中华按蚊被处理８代，Ｌｅ５０由０．０２５６ｐｐｍ至第４代（Ｆ３）时的０．０４８ｐｐｍ，抗性指数为１．８８，其后逐比下降至处理起点水平上波动。溴氰菊酯与增效醚混用后，毒效明显增加，表明多功能氧化酶活力增强是拟除虫菊酯类抗性机理之一。 Culex pipiens pallens were crossed with deltamethrin for 10 generations, the Le50 increased from 0.0402ppm to 21.2738ppm, the resistance was up to 529.20 times, and the resistance increased exponentially. Anopheles sinensis was treated for 8 generations and Le50 was 0 .0256 ppm up to 0.048 ppm at the fourth generation (F3), with a resistance index of 1.88, after which it fluctuated logically from start to finish. The combination of deltamethrin and piperine significantly increased the toxic effect, suggesting that enhanced multifunctional oxidase activity is one of the mechanisms of pyrethroid resistance.