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目的:探讨不同剂量尿激酶治疗包裹性胸腔积液疗效。方法:81例结核性包裹性胸腔积液作为研究对象,按患者入院先后顺序并完成治疗者分为两组。A组45例,常规抽液并注射尿激酶40万U/次,3次/周;B组36例,常规抽液并注射尿激酶10万U/次,3次/周。两组化疗方案为2HRZE/6HR治疗。结果:1个月:A组胸腔积液控制率91.1%,显效36例(80%),有效5例(11.1%),无效4例(8.9%);8个月总有效率100%。B组:1个月胸液控制率66.6%,显效3例(8.3%),有效21例(58.3%),无效12例(33.3%);8个月总有效率83.3%。结论:包裹性胸腔积液尿激酶注入量不同,效果存在明显差异。
Objective: To investigate the efficacy of different doses of urokinase in the treatment of encapsulated pleural effusion. Methods: 81 cases of tuberculous pleural effusion as the research object, according to the patient admission sequence and complete the treatment were divided into two groups. A group of 45 cases, routine pumping and urokinase 400000 U / times, 3 times / week; B group 36 cases, routine pumping fluid and injection of urokinase 100,000 U / times, 3 times / week. Two groups of chemotherapy regimens for the treatment of 2HRZE / 6HR. Results: One month, the control rate of pleural effusion in group A was 91.1%, markedly effective in 36 cases (80%), effective in 5 cases (11.1%) and ineffective in 4 cases (8.9%). The total effective rate in 8 months was 100%. In group B, the control rate of pleural effusion in one month was 66.6%, markedly effective in 3 cases (8.3%), effective in 21 cases (58.3%) and ineffective in 12 cases (33.3%). The total effective rate in 8 months was 83.3%. CONCLUSION: The amount of urokinase injected into pleural effusion is different, the effect is obviously different.