氯霉素眼药水是临床常用的滴眼剂之一,对砂眼、角膜炎、结膜炎等眼疾,具有良好疗效而且性质稳定,因此是医疗单位常配制的一种眼用制剂。虽然氯霉素眼药水是很稳定的,但在使用过程中,发现刺激性不断增加。当时配制的氯霉素眼药水,并没有什么刺激性,但放置几天后,滴入眼内感到痛疼,很不舒适。对这个问题,我们对氯霉素的配方、酸硷度、含量等方面作了分析观察。 Chloramphenicol eye drops is one of the eye drops commonly used in clinical practice, eye diseases such as trachoma, keratitis, conjunctivitis, has a good effect and stable nature, it is often formulated by the medical unit an ophthalmic preparation. Although chloramphenicol eye drops are very stable, but in the course of use, found that irritation increased. Chloramphenicol eye drops at the time of preparation, and no irritation, but after a few days, dropping into the eyes feel pain, very uncomfortable. On this issue, we chloramphenicol formula, pH, content and other aspects were analyzed and observed.