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目的:探讨慢性阻塞性肺疾病合并呼吸衰竭的临床疗效。方法:选取2012年12月至2014年12月本院收治的慢性阻塞性肺疾病合并呼吸衰竭患者80例,随机分成两组,每组40例,对照组实施常规治疗,而观察组进行无创正压通气治疗,观察患者治疗效果。结果:经治疗后,观察组患者的插管率以及病死率明显低于对照组,实际住院时间明显少于对照组。观察组的pH值、动脉氧气压力(PaO_2)、动脉血二氧化碳分压(PaCO_2)改善情况以及肺功能分级情况明显优于对照组,差异具有统计学意义(P<0.05)。结论:对慢性阻塞性肺疾病合并呼吸衰竭患者在常规治疗的基础上进行无创正压通气治疗,能够有效降低患者的插管率以及病死率,减少住院时间,改善pH值、PaO_2、PaCO_2以及肺功能分级。
Objective: To investigate the clinical efficacy of chronic obstructive pulmonary disease combined with respiratory failure. Methods: Eighty patients with chronic obstructive pulmonary disease and respiratory failure admitted to our hospital from December 2012 to December 2014 were randomly divided into two groups (n = 40 in each group). The control group was treated with conventional therapy while the observation group with noninvasive positive Pressure ventilation treatment, observation of patient treatment. Results: After treatment, the intubation rate and mortality in the observation group were significantly lower than those in the control group, and the actual length of hospital stay was significantly less than that of the control group. The observation group’s pH value, arterial oxygen pressure (PaO_2), arterial partial pressure of carbon dioxide (PaCO_2) improvement and pulmonary function classification were significantly better than the control group, the difference was statistically significant (P <0.05). CONCLUSIONS: Noninvasive positive pressure ventilation in patients with chronic obstructive pulmonary disease and respiratory failure can reduce intubation rate and mortality, reduce hospitalization time, improve pH, PaO 2, PaCO 2 and lung Functional classification.