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0 引言 肝癌恶性程度极高 ,在我国有着较高发病率和死亡率 ,迄今尚无理想的治疗手段 .随着现代分子生物学和免疫学的发展 ,基因工程抗体的诞生为肿瘤的诊断和治疗带来了希望 ,尤其是单链抗体的应用成为肿瘤免疫基因治疗的热点我们利用本室克隆的抗肝癌单链抗体 (s Fv)基因与
0 Introduction The degree of malignancy of liver cancer is extremely high, and it has high morbidity and mortality in China. So far, there is no ideal treatment. With the development of modern molecular biology and immunology, the birth of genetic engineering antibody is the diagnosis and treatment of cancer. Brought hope, especially the application of single-chain antibody has become a hot spot for tumor immunogene therapy. We have used the cloned anti-hepatoma single-chain antibody (s Fv) gene and