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目的:探讨强心甙的结构与抗疱疹病毒活性的关系。 方法:蟾蜍灵(Bufalin)及洋地黄毒甙元(Digitoxigenin)共合成了14种糖苷,并比较了它们的抗疱疹剂量(AHD)及细胞毒性。结果见附表。
Objective: To investigate the relationship between the structure of cardiac glycosides and anti-herpesvirus activity. Methods: Bufalin and digitoxigenin were used to synthesize 14 kinds of glycosides and compared their anti-herpes dosage (AHD) and cytotoxicity. The results see the schedule.