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氟中毒体内自由基水平的升高是致机体损伤机制中的重要环节~([1,2])。大量的研究均表明,长期高氟摄入会导致体内自由基水平升高,抗氧化酶及抗氧化能力下降。因此,有研究者认为过量的氟摄入可促使机体发生氧化应激反应~([3-7])。海参多糖(polysaccharides from the sea cucumber,PSU)是从海洋生物海参中提取的活性物质,在医药领域有巨大应用潜力,海参多糖已
Fluorosis increased the level of free radicals in the body is an important part of the mechanism of injury ~ ([1,2]). A large number of studies have shown that long-term high fluoride intake will lead to elevated levels of free radicals, antioxidant enzymes and antioxidant capacity decreased. Therefore, some researchers believe that excessive fluoride intake can promote the body’s oxidative stress ~ ([3-7]). Polysaccharides from the sea cucumber (PSU) is an active substance extracted from sea cucumber, which has great potential in the field of medicine.