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目的分析老年脑微出血(CMBs)的临床特点及危险因素。方法选取2010年2月～2012年2月解放军总医院南楼神经内科住院患者217例,年龄60~96岁,平均(81±6)岁。采用1.5T核磁共振扫描仪行常规磁共振及三维梯度回波序列检查,记录CMBs病灶数。结果 CMBs总检出率为39.2%,随着年龄增长,CMBs检出率逐步增高,≥90岁可高达50%。多元回归分析显示:年龄(95%CI 1.202~2.322,P=0.014)、高血压(95%CI 1.143~4.927,P=0.020)和脑梗死病史(95%CI 1.108~4.439,P=0.024)与老年CMBs密切相关。结论≥60岁患者中,CMBs检出率接近40%,年龄、高血压及脑梗死病史是老年CMBs独立危险因素。
Objective To analyze the clinical features and risk factors of cerebral micro-hemorrhage (CMBs) in the elderly. Methods A total of 217 inpatients with neurosurgery from the south hospital of Chinese PLA General Hospital from February 2010 to February 2012 were selected, aged from 60 to 96 years, with an average of (81 ± 6) years. 1.5T nuclear magnetic resonance scanner with conventional magnetic resonance and three-dimensional gradient echo sequence check, record the number of CMBs lesions. Results The overall detection rate of CMBs was 39.2%. With the increase of age, the detection rate of CMBs gradually increased, reaching as high as 50% at 90 years of age. Multiple regression analysis showed that age (95% CI 1.202-2.232, P = 0.014), hypertension (95% CI 1.143-4.927, P = 0.020) and history of cerebral infarction (95% CI 1.108-4.439, P = 0.024) Elderly CMBs are closely related. Conclusion The detection rate of CMBs in patients ≥60 years old is close to 40%, and the history of age, hypertension and cerebral infarction are independent risk factors of CMBs in elderly.