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为进一步研究HLA与银屑病性关节炎及其亚型的关系,作者对60例(男29,女31例,均为白种人)银屑病性关节炎患者进行了HLA分型.所有患者IgM和IgG类风湿因子阴性.临床受累关节作X线摄片,HLA-A、B抗原用标准淋巴细胞毒方法测定,HLA-DR抗原用对B细胞的延长淋巴细胞毒方法测定.正常人对照者Ⅰ类抗原375例,Ⅱ类抗原163例,均为白种献血员和实验室成员.患者共分6个亚组:(1)只有外周关节炎(PAO);(2)外周关节炎伴或不伴有中轴性病变,但不符合脊椎炎罗马标准
To further investigate the relationship between HLA and psoriatic arthritis and its subtypes, the authors performed HLA typing on 60 patients (29 males and 31 females, all Caucasian) with psoriatic arthritis. All Patients with negative IgM and IgG rheumatoid factor clinical joint involvement for X-ray, HLA-A, B antigen was determined by standard lymphocytotoxicity assay, HLA-DR antigen with the B cell prolonged lymphocytotoxicity assay.Normal individuals 375 cases of type I antigens and 163 cases of type II antigens were white blood donors and laboratory members.The patients were divided into six subgroups: (1) only peripheral arthritis (PAO); (2) peripheral arthritis With or without axial lesions, but does not meet the Rome spine inflammation standards