目的描述陕西省汉族PCI术后人群的细胞色素2C19(CYP2C19)基因型分布特征。方法采用个体化基因诊断芯片技术对1 220例陕西汉族PCI术后人群进行CYP2C19基因分型检测。结果陕西汉族术后人群中男性野生基因型比例为34.02%(*1*1),突变杂合子基因型比例为33.61%(*1*2和1*3),突变纯合子基因型比例为9.43%(*2*2、*2*3和*3*3)。女性野生基因型比例为9.34%(*1*1),突变杂合子基因型比例为11.23%(*1*2和1*3),突变纯合子基因型比例为2.38%(*2*2、*2*3和*3*3)。结论陕西汉族PCI术后人群CYP2C19基因多态性以野生型纯合子*1*1和突变杂合子*1*2为主。 Objective To describe the distribution of cytochrome 2C19 (CYP2C19) genotype in Han population of Han nationality in Shaanxi Province. Methods CYP2C19 genotyping was performed in 1220 Han Chinese patients with postoperative PCI using a personalized gene diagnostic chip technique. Results The proportion of male genotypes in Han Han population was 34.02% (* 1 * 1), the heterozygous heterozygote genotypes were 33.61% (* 1 * 2 and 1 * 3), and the percentage of homozygous mutant genotypes was 9.43 % (* 2 * 2, * 2 * 3 and * 3 * 3). The percentage of genotypes of wild type was 9.34% (* 1 * 1) in wild type, 11.23% (* 1 * 2 and 1 * 3) in heterozygous heterozygous genotypes, and 2.38% (* 2 * * 2 * 3 and * 3 * 3). Conclusions CYP2C19 polymorphism in Han population of Han nationality in Han population is mainly wild type homozygote * 1 * 1 and mutant heterozygote * 1 * 2.