本文对藻胆色素与半胱氨酸残基的结合反应进行了试验,通过藻红胆素二甲酯、藻蓝胆素二甲酯分别与半胱氨酸甲酯、谷胱甘肽(还原型)二甲酯的反应得到了一些与藻胆蛋白上发色团具有相同共价结构的化合物。这些化合物与其他胆色素类化合物不同的是有很强的荧光发射和圆二色效应。化合物的圆二色效应分析表明,藻胆色素与半胱氨酸甲酯、谷胱甘肽(还原型)二甲酯反应时得到的产量较大的异构体与藻胆蛋白上的发色团具有相同的立体结构。 In this paper, the binding reaction between phycobiliproteins and cysteine ​​residues was tested. Through the reaction of dimethyl-phycocyanine, dimethyl-phycocyanolate and cysteine ​​methyl ester, glutathione Prototype) dimethyl ester gave some compounds with the same covalent structure as the chromophore on phycobiliproteins. Unlike other biliary compounds, these compounds have strong fluorescence emission and circular dichroism. The circular dichroism analysis of the compounds showed that the larger isomers of the phycobiliproteins reacted with the methyl ester of cysteine ​​methyl ester and glutathione (reduced form) and the color of the phycobiliproteins Mission has the same three-dimensional structure.