患者男,18岁,因颜面、下肢浮肿月余而就诊。患者少年时期曾患精神分裂症经“治愈”停药至今,否认肾病史。蛋白,红细胞少许,血细胞少许,透明管型少许,颗粒管型(+);血Cr113.15umol/L,BUN3.93mmol/L,CO_2CP29.2mmpl/L;24小时尿蛋白9g;诊断为原发性肾病综合征。给予强的松,抗高凝,利尿消肿,中药等治疗。2周后尿量增多,浮肿开始消减,尿蛋白定性(-),当强的松用到第26天时,患者出现精神异常而放弃激素治疗,到某精神病院治疗精神病。一个多月后,精神症状被控制,但肾病综合征又复发而再次求治,再给予初次治疗方案重新治疗,8周后 Male patient, 18 years old, due to face, lower extremity edema and treatment. Patients suffering from schizophrenia as a teenager “cure” withdrawal so far, denied the history of kidney disease. Protein, red blood cells a little, a little blood cells, a little transparent tube, granular tube (+); blood Cr113.15umol / L, BUN3.93mmol / L, CO_2CP29.2mmpl / L; 24 hours urinary protein 9g; diagnosis of primary Nephrotic syndrome. Given prednisone, anti-hypercoagulability, diuretic swelling, traditional Chinese medicine and other treatment. 2 weeks after the increase in urine output, edema began to diminish, qualitative urine protein (-), when prednisone used on the 26th day, patients with mental disorders gave up hormone therapy, to a mental hospital for the treatment of mental illness. More than a month later, the psychiatric symptoms were controlled, nephrotic syndrome was recurred and treated again, and then given the first treatment regimen re-treatment, 8 weeks later