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龙胆泻肝汤(YS-Tang)是一传统中药方剂,在韩国用于治疗多种病毒性疾病。一氧化氮(NO)是 L-精氨酸胍基末端的氮原子在一氧化氮合成酶作用下生成的一高度活泼的分子,最近报道它对人和鼠有抗病毒作用。为证实 YS-Tang 的抗病毒机理,作者研究了其水浸膏(26.25 g 浸膏含龙胆草、柴胡、泽泻各3.75 g,木通、车前子、地黄、栀子、黄芩、当归、甘草、茯苓各1.875 g)对小鼠腹腔巨噬细
Longdanxiegan Decoction (YS-Tang) is a traditional Chinese herbal formula used to treat a variety of viral diseases in South Korea. Nitric oxide (NO) is a highly reactive molecule produced by nitric oxide synthase at the terminal nitrogen of L-arginine oxime. It has recently been reported to have antiviral effects in humans and mice. In order to confirm the antiviral mechanism of YS-Tang, the authors studied its water extract (26.25 g extract containing 3.75 g each of gentian, Bupleurum, Alisma, Mutong, Plantain fruit, Rehmannia glutinosa, Gardenia jasminoides, Radix Astragali, Angelica sinensis, licorice, and wolfberry each 1.875 g) peritoneal macrophages in mice