对埃及产短尖灯心草Juncus acutus L.的根茎进行植化研究,分离出一个新的菲类化合物juncutol (1)和3个相关的化合物(2～4)。首次研究了它们对脂多糖(LPS)刺激的鼠RAW 264.7巨噬细胞株中诱生型一氧化氮合酶(iNOS)蛋白表达的抑制作用,从而证明了在远东将灯心草属草药作为传统的解热药和抗炎药与其抗炎活性的相关性。 The roots of Juncus acutus L., an Egyptian rush, was subjected to the planting study to isolate a new phenanthrene compound juncutol (1) and three related compounds (2-4). For the first time, their inhibitory effect on the expression of inducible nitric oxide synthase (iNOS) protein in the rat RAW 264.7 macrophage cell strain stimulated by lipopolysaccharide (LPS) was studied, thus demonstrating that the genus Ural herb was used as a traditional solution in the Far East. The correlation between thermal drugs and anti-inflammatory drugs and their anti-inflammatory activity.