间歇的伴有瞳孔缩小的双眼集合和调节性眼震常常被认为是功能性表现.文献上偶尔报导这种改变伴有中枢神经系统器质性疾病的病例,但很少引起注意,本文报告的这一体征是因苯妥英钠过量而引起中毒性脑病所致. Intermittent clumping binocular sets and accommodative nystagmus are often considered functional manifestations of this type of change, incidentally reported in the literature with organic disease of the central nervous system, but seldom draw attention, as reported in this paper This sign is due to phenytoin excess caused by toxic encephalopathy.