羧酸或其酯是至少由一个C1-C10的饱和醇类和一氧化碳反应制备而成。这个过程需要在铱催化剂,含卤的助催化剂,水及溶剂条件下完成。助催化剂、酯、醇和水的浓度在反应过程中很重要,分别是≤10%,2-4%,≤10%。羧酸也作为一种溶剂。催化剂系统首选由HI或酸的前体制备的羰基铱或氧化铱,该过程发生在惰性气体或空气介质中。HI和铱催化剂的摩尔比是1:100。 The carboxylic acid or ester thereof is prepared by the reaction of at least one C1-C10 saturated alcohol with carbon monoxide. This process needs to be done under iridium catalyst, halogen-containing cocatalyst, water and solvent. Concentrations of cocatalyst, ester, alcohol and water are important during the reaction, and are respectively ≤10%, 2-4%, ≤10%. Carboxylic acids also act as a solvent. The catalyst system is preferably carbonyl iridium or iridium oxide prepared from HI or an acid precursor which occurs in an inert gas or air medium. The molar ratio of HI to iridium catalyst is 1: 100.