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应用脉冲多普勒超声法测定39例较中度高血压病(EH)患者和正常人左室舒张功能各项参数,进行相关性分析,结果显示:EH组PVE变小,PVA增大,PVE/PVA比值缩小,IRT延长,LVmass和LVmI增加,LAD增大,均与对照组相差显著(P<0.05~0001)。PVE/PVA,IRT和LVmass均与MAP呈相关性(r=-0.37,0.37,0.41);LVmass与PVE/PVA,IRT,LAD和LVmI相关性好(r=-0.41,0.38,0.53,0.96);且IRT与PVE/PVA呈负相关(r=-0.43)。研究表明,EH患者早期常出现左室舒张功能异常,测量PVE/PVA及IRT便捷、直观。左室舒张功能受累还常伴有左房内径扩大和LVmI增加。
The parameters of left ventricular diastolic function in 39 patients with moderate hypertension (EH) and normal persons were determined by pulsed-wave Doppler ultrasonography and the correlation analysis was made. The results showed that PVE in EH group was smaller, PVA was increased, PVE / PVA ratio decreased, IRT prolonged, LVmass and LVmI increased, LAD increased, both with the significant difference (P <0.05 ~ 0001). PVE / PVA, IRT and LVmass were correlated with MAP (r = -0.37,0.37,0.41); LVmass was correlated with PVE / PVA, IRT, LAD and LVmI (r = -0.41, 0.38,0.53,0.96); And IRT and PVE / PVA was negatively correlated (r = -0.43). Studies have shown that patients with early EH often appear abnormal left ventricular diastolic function, measurement of PVE / PVA and IRT convenient and intuitive. Diastolic left ventricular involvement is also often accompanied by left atrial enlargement and LVmI increased.