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恶性肝细胞癌在新加坡通常是癌症的死亡原因之一,诊断是根据测到的AFP高值。可是在该地区,患有这种肿瘤的病人有15%的AFP值是低于正常(18 ng/dl)。此外,另一种情况是,由于传染性乙型肝炎引起的肝脏坏死、再生性肝结节及正常妊娠期的AFP同样可以升至最高值,因而造成了诊断的困难。血清糖蛋白的研究(即血清α_1-抗胰蛋白酶、α-酸性糖蛋白和β_2-糖蛋白1的测定)、对肝炎和肝硬化的估计,肝细胞癌的识别、病情进展的监视及检测方法的筛选,都是极其有用的。本文所选病例是经组织学确诊的肝细胞癌患
Malignant hepatocellular carcinoma is usually one of the causes of cancer death in Singapore and the diagnosis is based on the high AFP measured. However, in this region, 15% of patients with this tumor have AFP values below normal (18 ng / dl). In addition, another situation is that due to hepatitis B-induced liver necrosis, regenerative liver nodules and normal pregnancy AFP can also be raised to the highest value, thus causing the diagnosis of difficulties. Serum glycoproteins (ie, serum alpha 1-antitrypsin, alpha-acid glycoprotein and beta 2-glycoprotein 1), estimates of hepatitis and cirrhosis, identification of hepatocellular carcinoma, surveillance and detection of disease progression The screening is extremely useful. Selected cases of this paper is histologically diagnosed hepatocellular carcinoma