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目的探讨老年结核性脑膜炎(结脑)并发中、重度脑积水的临床特征与影像学变化。方法回顾性分析经影像学证实的老年结脑并发中、重度脑积水35例。结果大脑导水管梗阻占829%,基底池粘连占200%。脑脊液(CSF)蛋白定量、白蛋白、IgG升高与脑积水有关。结论脑膜纤维蛋白渗出、粘连与老年性脑室变窄是造成脑积水的主要因素。CT与CSF中蛋白指标监测对脑积水的早期诊断、预后评估具有重要价值。
Objective To investigate the clinical features and imaging changes of elderly patients with tuberculous meningitis (tuberculous meningitis) complicated with moderate and severe hydrocephalus. Methods Retrospective analysis of 35 cases of moderate and severe hydrocephalus confirmed by imaging confirmed senile tuberculosis. Results The occlusion of the aqueduct of the brain accounted for 82.9%, and basal cell adhesion accounted for 20.0%. Cerebrospinal fluid (CSF) protein quantitation, albumin, elevated IgG and hydrocephalus. Conclusion The leakage of meningin fibrin, adhesions and narrowing of senile ventricles are the main factors that cause hydrocephalus. The monitoring of protein indexes in CT and CSF is of great value in the early diagnosis and prognosis evaluation of hydrocephalus.