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近年来,获得并筛选了大量合成或半合成的柔红霉素和阿霉素类似物,这些化合物可分为对糖部分作修饰和对配基部分作修饰的两类。
In recent years, a large number of synthetic or semi-synthetic daunorubicin and doxorubicin analogues have been obtained and screened. These compounds can be divided into two groups, which are the modification of the sugar moiety and the modification of the ligand moiety.