氟啶酸为一种新型广谱氮喹诺酮(azaquinolone),在体外,本品具有抗奈瑟氏淋球菌,包括产生青霉素酶的菌株的活性。作者评价了口服氟啶酸400mg和肌注头孢三嗪噻肟250mg治疗无并发症生殖器奈瑟氏淋球菌感染的安全性及疗效。 57例病人,其中6例(12.5％)为产生青霉素酶的菌株,11例(23％)合并沙眼衣原体感染。病 Fluoric acid is a new broad-spectrum quinolone (azaquinolone) which has in vitro activity against Neisseria gonorrhoeae, including strains producing penicillinase. The authors evaluated the safety and efficacy of oral administration of 400 mg of flunisolide and 250 mg of cefotaxime triadimefon in the treatment of Neisseria gonorrhoeae infection in complication-free genitalia. Sixty-seven patients (12.5%) were penicillinase-producing strains and 11 (23%) were infected with C. trachomatis. disease