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目的 总结翼点入路显微外科手术治疗哑铃形垂体腺瘤的经验。方法 27例病人均经翼点入路开颅,在显微镜下解剖基底池,利用脑的自然间隙显露并切除肿瘤。结果 27例病人中获全切除22例(占81.5%),其余5例获次全切除(占18.5%),无手术后死亡病例。对全部病例进行了1~4.5年(平均1.8年)随访观察,全切者经MRI复查21例未见复发,1例复发后行伽玛刀治疗。结论 翼点入路可获得良好的鞍区显露,有助于大型或巨型腺瘤的全切,是治疗哑铃形垂体腺瘤的最佳手术入路。
Objective To summarize the experience of pterional approach microsurgery for treatment of dumbbell-shaped pituitary adenomas. Methods Twenty-seven patients underwent craniotomy through a pterional approach. The basement pool was dissected under a microscope. The brain was exposed and removed with the natural space. Results Twenty-two patients (81.5%) were totally resected in 27 patients. The remaining 5 patients received subtotal resection (18.5%) and no postoperative deaths. All patients were followed up for 1 to 4.5 years (mean, 1.8 years). All the patients who had undergone MRI had no recurrence in 21 cases, and 1 case had gamma knife after recurrence. Conclusion The pterional approach can obtain good saddle area exposure, which is helpful for the complete excision of large or giant adenomas. It is the best surgical approach for treatment of dumbbell-shaped pituitary adenomas.