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目的观察奥扎格雷钠联合注射用环磷腺苷葡胺治疗急性脑梗死临床疗效。方法 66例急性脑梗死患者随机分为治疗组和对照组,二组患者均给予一般治疗及常规治疗,治疗组另予奥扎格雷钠和环磷腺苷葡胺静脉滴注,疗程14d,治疗前后对二组患者神经功能缺损程度、血液流变学等指标进行比较。结果治疗组总有效率为90.9%,明显优于对照组66.6%(P<0.05);治疗后治疗组神经功能缺损评分等各项指标比较,差异有统计学意义(P<0.05)。结论奥扎格雷钠联合环磷腺苷葡胺治疗急性脑梗死疗效优于对照组。
Objective To observe the clinical efficacy of ozagrel combined with cyclophosphamide for the treatment of acute cerebral infarction. Methods Sixty-six patients with acute cerebral infarction were randomly divided into treatment group and control group. Patients in both groups were given general treatment and routine treatment. Ozagrel sodium and amidotime were also given intravenously in the treatment group for 14 days. Before and after the two groups of patients with neurological deficit, hemorheology and other indicators were compared. Results The total effective rate in the treatment group was 90.9%, which was significantly better than that in the control group (66.6%, P <0.05). There were significant differences in the indexes of neurological deficit in the treatment group after treatment (P <0.05). Conclusion Ozagrel combined with cyclophosphamide for the treatment of acute cerebral infarction is superior to the control group.