In recent years, land use/cover dynamic change has become a key subject that needs to be dealt with in the study of global environmental change. In this paper, remote sensing and geographic information systems (GIS) are integrated to monitor, map, and quantify the land use/cover change in the southern part of Iraq (Basrah Province was taken as a case) by using a 1:250000 mapping scale. Remote sensing and GIS software were used to classify Landsat TM in 1990 and Landsat ETM+ in 2003 imagery into five land use and land cover (LULC) classes: vegetation, sand, urban area, unused land, and water bodies. Supervised classification and normalized difference build-up index (NDBI) were used respectively to retrieve its urban boundary. An accuracy assessment was performed on the 2003 LULC map to determine the reliability of the map. Finally, GIS software was used to quantify and illustrate the various LULC conversions that took place over the 13-year span of time. Results showed that the urban area had increased by the rate of 1.2% per year, with area expansion from 3299.1 km2 in 1990 to 3 794.9 km2 in 2003. Large vegetation area in the north and southeast were converted into urban construction land. The land use/cover changes of Basrah Province were mainly caused by rapid development of the urban economy and population immigration from the countryside. In addition, the former government policy of “returning farmland to transportation and huge expansion in military camps” was the major driving force for vegetation land change. The paper concludes that remote sensing and GIS can be used to create LULC maps. It also notes that the maps generated can be used to delineate the changes that take place over time.