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目的观察血管内支架成形术治疗症状性椎动脉起始部狭窄的安全性及有效性。方法对52例症状性椎动脉起始部狭窄的患者行支架成形术治疗。对术后患者进行随访3～18个月,通过临床症状、数字减影血管造影(DSA)评价其疗效。结果 52例患者均成功植入球扩支架。术后造影显示狭窄程度改善明显,狭窄率从术前的(77±12)%下降到治疗后的(15±4)%。无1例发生严重并发症。在6个月的临床随访中,2例有新的TIA发作,但无新的脑梗死,DSA复查20例患者中2例有再狭窄,但没有症状,狭窄率均约50%。结论症状性椎动脉起始部狭窄的血管内支架植入术是安全、有效的,但其远期疗效还要作进一步随访研究。
Objective To observe the safety and efficacy of endovascular stenting in the treatment of symptomatic vertebral artery stenosis. Methods 52 cases of symptomatic vertebral artery stenosis patients underwent stenting. The postoperative patients were followed up for 3 to 18 months. The clinical symptoms and digital subtraction angiography (DSA) were used to evaluate the curative effect. Results All the 52 patients were successfully implanted into the stent. Postoperative angiography showed a significant improvement in stenosis with a reduction in stenosis from (77 ± 12)% before surgery to (15 ± 4)% after treatment. No one had serious complications. In the 6-month clinical follow-up, 2 patients had a new TIA episode but no new cerebral infarction. Two of the 20 patients underwent a DSA scan with restenosis but no symptoms and a stenosis rate of about 50%. Conclusions The stenting of symptomatic vertebral artery at the beginning of stenosis is safe and effective. However, its long-term efficacy should be further investigated.