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本文报告1例临床酷似大疱性类天疱疮的大庖性疥疮。男,73岁,在胸、背、臀、四肢、阴茎出现瘙痒性结痂性发疹4个月,四肢反复出现水疱2个月。曾用强的松80mg/d治疗14天,后逐渐减量,6周后停药,但水疱仍存在并反复出现。体检见结痂性皮损、炎性斑块和一些疱壁紧张、部分呈出血性的水疱,很像大疱性类天疱疮,但在皮损的搔抓物中发现了疥螨。大疱活组织检查示表皮下水疱,疱腔及表皮下可见大量嗜酸粒细胞,在皮损边界处的乳头层顶部可见真表皮裂隙,PAS染色示疱壁底部基板完整,
This article reports 1 case of clinical resembles bullous pemphigoid big scabies scabies. Male, 73 years old, in the chest, back, buttocks, limbs, penis pruritus scabrous rash 4 months, blisters repeated limbs for 2 months. Had used prednisone 80mg / d for 14 days, then gradually reduced, 6 weeks after withdrawal, but the blister is still present and repeated. Physical examination to see scabby lesions, inflammatory plaque and some vesicular wall tension, some were bloody blisters, like bullous pemphigoid, but found in the scratched skin lesions scabies mites. Bulb biopsy showed subepidermal blisters, blisters and epidermis, a large number of eosinophils can be seen in the skin lesions at the junction of the dermis at the top of the dermis visible true dermatome, PAS staining blister wall at the bottom of the substrate integrity,