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目的探讨磁敏感加权成像(SWI)在新生儿缺氧缺血性脑病(HIE)诊断中的价值。方法选取HIE新生儿60例,采用德国Siemens公司Avanto 1.5T超导型MR扫描仪,检查前30 min给予10%水合氯醛口服或灌肠(0.3~0.5 ml/kg),使患儿在睡眠状态下完成检查。常规行横轴位T1WI、T2WI和DWI扫描,均增加横轴位SWI扫描。比较头颅常规MRI序列与SWI序列检查对病灶的检出率,部位及性质。结果 SWI检出的脑微出血病灶数量最多,与T1WI、T2WI、DWI检出率比较,差异均具有统计学意义(均<0.01),在病灶大小、范围及边界清晰度显示方面,SWI均明显优于T1WI、T2WI和DWI。结论 SWI在HIE微小出血灶的数量及面积的显示上优于常规序列,具有明显优势,有助于更好地评估HIE损害的程度及预后,具有一定的推广价值。
Objective To investigate the value of magnetic susceptibility weighted imaging (SWI) in the diagnosis of neonatal hypoxic-ischemic encephalopathy (HIE). Methods Sixty newborns with HIE were selected. Avanto 1.5T superconducting MR scanner was used in Siemens Company of Germany. 10% chloral hydrate orally or enema (0.3-0.5 ml / kg) was given 30 min before the examination, Complete the inspection. Conventional horizontal axis T1WI, T2WI and DWI scan, increase the horizontal axis of the SWI scan. Compare the detection rate, location and nature of lesion with routine craniocerebral MRI and SWI. Results The number of cerebral micro-hemorrhagic lesions detected by SWI was the most, which was significantly different from that of T1WI, T2WI and DWI (all <0.01), and the SWI was obvious in size, range and boundary definition Better than T1WI, T2WI and DWI. Conclusion SWI is superior to conventional sequences in displaying the number and area of micro-hemorrhagic foci of HIE. It has obvious advantages and helps to evaluate the extent and prognosis of HIE lesion better. It has some promotion value.