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22例老年女性Graves病患者治疗前血清钙、碱性磷酸酶(AKP)及24小时尿钙、磷排量均显著高于对照组(P<0.05),骨密度(BMD)显著低于对照组(P<0.05)。经治疗2~3个月甲状腺机能亢进(甲亢)基本控制后,血清钙及24小时尿钙、磷排量随之恢复正常,但血AKP、BMD直到治疗12~18个月才恢复正常。本文对老年女性Graves病治疗前、后BMD及钙、磷代谢的变化进行了初步讨论。
The serum Ca, Alkaline phosphatase (AKP) and 24-hour urinary calcium and phosphorus excretion of 22 elderly female patients with Graves’ disease were significantly higher than those of the control group (P <0.05), and their bone mineral density (BMD) Control group (P <0.05). After 2 to 3 months of treatment of hyperthyroidism (hyperthyroidism) basic control, serum calcium and 24-hour urine calcium and phosphorus returned to normal, but the blood AKP, BMD until 12 to 18 months of treatment before returning to normal. In this paper, the changes of BMD, calcium and phosphorus metabolism in elderly women with Graves disease before and after treatment were discussed.