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目的 评价血液透析患者庚型肝炎(HGV)、乙型肝炎(HBV)、丙型肝炎(HCV)感染状况及对肝功能的影响。方法 采用逆转录聚合酶链反应(RT-PCR)法对68例血液透析患者血清标本进行检测。结果 68例患者血清中有6例HGVRNA阳性(88%)。这6例患者同时重叠HCV感染,其中2例为HBV,HCV,HGV重叠感染。13例HCVRNA阳性(191%),9例HBVDNA阳性(132%)。结论 血透患者是HGV感染的高危人群,输血为血透患者感染HGV,HCV,HBV的主要途径,但也存在医源性传播的可能
Objective To evaluate the effect of hepatitis G (HGV), Hepatitis B (HBV) and Hepatitis C (HCV) infection on hepatic function in hemodialysis patients. Methods Serum samples from 68 patients with hemodialysis were detected by reverse transcription-polymerase chain reaction (RT-PCR). Results Six of the 68 patients had positive HGV RNA (88%). These 6 patients also overlap with HCV infection, including 2 cases of HBV, HCV, HGV overlap infection. Thirteen HCV RNA positive (191%) and nine HBVDNA positive (132%). Conclusion Hemodialysis patients are the high risk population of HGV infection. Blood transfusions are the main pathways of HGV, HCV and HBV infection in hemodialysis patients, but there is also the possibility of iatrogenic transmission