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本文观察了r线全身照射后,大鼠骨髓、十二指肠和小脑微血管通透性的改变。结果表明:正常时骨髓微血管通透性最高,十二指肠次之,小脑最低。照后骨髓微血管通透亢进发生早、增加快、变化大、恢复慢,主要发生在血窦;照后十二指肠微血管通透亢进发生较早、增加较快、变化较大、恢复较快,主要发生在肠绒毛的毛细血管和细静脉;照后小脑微血管通透性变化较小,在400.0Gy组可见通透亢进,主要发生在小脑皮质的毛细血管。所有这三个脏器微血管通透亢进部位,实质细胞的退变明显加重。说明微血管邇透亢进可明显加重实质细胞的损伤,而实质细胞的再生修复,就发生在微血管通透恢复,基底背景较清净地方。说明:照后骨髓、十二指肠、小脑微血管通透性的改变,在造血型、胃肠型和脑型急性放射病的发病机理上有重要意义。
This article observed the r line after whole body irradiation, the rat bone marrow, duodenum and cerebellar capillary permeability changes. The results showed that: the normal bone marrow capillary permeability, followed by the duodenum, cerebellar lowest. According to the photo, the hyperplasia of bone marrow microvessels occurred early, increased rapidly, changed greatly and recovered slowly, mainly occurred in the sinusoid. According to the results, the duodenal capillary permeability hyperfunction occurred earlier and faster, with more changes and faster recovery , Mainly in the villi of the capillaries and veins; according to the changes of cerebellar microvessel permeability was small, 40000Gy group visible hyperthyroidism, mainly in the cerebellar cortex of the capillaries. All three organ microvascular permeability hyperthyroidism site, degeneration of parenchymal cells significantly increased. Explanations of micro-vascular hyperactivity may significantly aggravate the parenchymal cell injury, and parenchymal cell regeneration and repair occurred in the recovery of microvascular permeability, the basal background cleaner. Description: According to the marrow, duodenum, cerebellar microvascular permeability changes in the hematopoietic, gastrointestinal and cerebral acute radiation disease pathogenesis is important.