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1982年以来,已有两篇综合报道描述了放射性药物的相互作用或它们所引起的不良反应。Cordova 等人列举了USP、SNM 以及FDA 自1976年以来已报告的药物反应数量。此文中,所有的反应由~(99m)Tc 标记的放射性药物引起的仅3例,其中1例由~(99m)Tc-MDP 引起。本文对该病例加以报道,作者认为该病例可能是患者对MDP 的典型反应。病例报告:患者女性,60岁,1980年因患乳腺癌,做了左侧乳房切除术。1983年4月,在X 线片上出现多处肺转移。同年4月用MDP 做骨扫描,显示在胸骨、腰椎及左侧坐骨有多处转移。扫描后48小时,感到咽
Since 1982, there have been two comprehensive reports describing the interactions of radiopharmaceuticals or the adverse reactions they cause. Cordova et al. Cite USP, SNM, and the number of reported drug reactions by the FDA since 1976. In this article, all the reactions were caused by ~ (99m) Tc-labeled radiopharmaceuticals, with only one being caused by ~ (99m) Tc-MDP. This article reports the case, the authors believe the case may be the typical response of patients to MDP. Case Report: Female patient, 60 years old, suffering from breast cancer in 1980 and having a left mastectomy. April 1983, there are many lung metastases on the X-ray film. In April the same year with the MDP bone scan, showing the sternal, lumbar and left ischial multiple metastasis. 48 hours after the scan, feel pharynx