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目的：考核人群接种ＨＦＲＳ（Ｉ型）灭活疫苗后３年内防病效果。方法：比较受试期间接种组和对照组ＨＦＲＳ发病情况。结果：第１年接种组种后２月内即１１～１２月间未发生ＨＦＲＳ病人，对照组发病５例，发病率９２．８５／１０万，疫苗保护率１００％；第２年全年接种组发病２例，发病率４１．０６／１０万，对照组发５例，发病率９２．８５／１０万，疫苗保护率５５．７８％；种后第３年接种组未发生ＨＦＲＳ病人，对照组发生２例，发病率３７．１４／１０万，疫苗保护率１００％。本研究为Ｉ型ＨＦＲＳ疫苗在姬鼠型疫区的推广使用提供了科学依据
OBJECTIVE: To evaluate the anti-pathogenic efficacy of HFRS (Type I) inactivated vaccines within 3 years after population vaccination. Methods: The incidence of HFRS in vaccinated and control groups during the trial period was compared. Results: In the first year of vaccination group, HFRS patients did not occur within 2 months after 11 ~ 12 months. In the control group, 5 cases were found, the incidence rate was 92.85 / 100000, the vaccine protection rate was 100%; the second year of annual vaccination The incidence of 2 cases was 41.06 / 100000 in control group and 5 cases in control group, the incidence rate was 92.85 / 100000, the protection rate of vaccine was 55.78%. In the third year after inoculation group, HFRS patients did not occur, Group occurred in 2 cases, the incidence rate of 37.14 / 100000, vaccine protection rate of 100%. This study provided a scientific basis for the popularization and application of type I HFRS vaccine in the region of Apodemus agie