乙型慢性活动性肝炎、肝硬化病程中黄疸迅速加深,血清总胆红素(STB)超过10mg%,是病情严重的重要标志之一。这种病例根据临床、病理可区分为慢活肝胆汁郁积和慢性重症肝炎。近几年来我们采用中西医结合治疗,明显地改善了慢活肝胆汁郁积的预后,而慢性重症肝炎死亡率却高达84～100%。但是目前对二者的诊断与鉴别诊断尚有一定的困难。本文旨在通过76例分析,提出二者的诊断、鉴别诊断要点,供同道参考。 B chronic active hepatitis, jaundice in the course of liver cirrhosis deepened rapidly, serum total bilirubin (STB) more than 10mg%, is one of the important signs of a serious condition. This case based on clinical, pathological can be divided into chronic liver cholestasis and chronic severe hepatitis. In recent years, we use traditional Chinese and Western medicine treatment, significantly improved the prognosis of chronic active liver cholestasis, and chronic severe hepatitis mortality rate as high as 84 to 100%. However, there is still some difficulty in the diagnosis and differential diagnosis between the two. This article aims to pass 76 cases of analysis, the two proposed diagnosis, differential diagnosis points for fellow reference.