论文部分内容阅读
概念与命名 起源于胰岛A细胞的胰高糖素瘤,越来越引起人们的重视。1942年皮科医生Beck-er在描述内脏恶性肿瘤与皮肤病变的关系时,报告1例54岁患者为胰岛A细胞瘤,并伴一种特殊的皮肤改变,当时曾以皮肤对肿瘤转移过程的反应来解释。1966年McGav-ran等提出由功能性胰岛A细胞所致的高胰高糖素血症,至1974年才由Mallinson等将该病命名为胰高糖素瘤综合征。本病是以对称性,游走性、周期发作性的红斑、贫血、糖尿病和体重减轻为特征。本文作者对137例资料较完整的病例综述如下。
The concept and nomenclature originated from pancreatic islet A cells of glucagon tumor, more and more aroused people’s attention. 1942 pico doctor Beck-er in describing the relationship between visceral malignancies and skin lesions, reported a 54-year-old patient with islet A cell tumor, accompanied by a special kind of skin change, when the skin has been the process of tumor metastasis Reaction to explain. 1966 McGav-ran put forward by the functional islet A cells caused by hyperglycemia, until 1974 by Mallinson et al the disease named glucagon syndrome. The disease is characterized by symmetry, mobility, periodic episodes of erythema, anemia, diabetes and weight loss. The author of the 137 cases of more complete data are summarized below.