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目的探讨新型免疫抑制剂MMF联合肾上腺皮质激素治疗狼疮肾炎临床疗效。方法将LN分为两组分别应用MMF、CTX并进行疗效对比。结果MMF组总有效率90%,CTX组总有效率63.3%两组比较有显著差异性(P<0.05)。结论MMF在治疗狼疮肾炎疗效明显。
Objective To investigate the clinical effect of new immunosuppressant MMF and adrenal cortex hormones in the treatment of lupus nephritis. Methods LN was divided into two groups, respectively, the application of MMF, CTX and efficacy comparison. Results The total effective rate was 90% in MMF group and 63.3% in CTX group. There was significant difference between the two groups (P <0.05). Conclusion MMF is effective in treating lupus nephritis.