皮肤桥蛋白是新近发现的分子量为 2 2kD的富含酪氨酸的蛋白质 ,由氨基末端酪氨酸富集区及随后三个相同的结构域构成。它在细胞外基质中分布广泛 ,具有结合蛋白聚糖、细胞、胶原蛋白及促进细胞粘附、胶原纤维合成的性质 ,是细胞外基质中的一种多功能蛋白质 ,在细胞、基质之间的相互作用及基质组装过程中具有重要作用。 Skin-bridge protein is a newly discovered tyrosine-rich protein with a molecular weight of 22 kD, consisting of an amino-terminal tyrosine-rich region followed by three identical domains. It is widely distributed in the extracellular matrix and has the properties of binding to proteoglycans, cells, collagen, and promoting cell adhesion and collagen synthesis. It is a multifunctional protein in the extracellular matrix, Interaction and matrix assembly process has an important role.