论文部分内容阅读
目的调查甘肃省武威市农村居民甲型肝炎病毒(HAV)和乙型肝炎病毒(HBV)的流行状况。方法采用随机抽样方法调查4个乡镇539人;ELISA法检测调查人群血清中抗-HAV IgG和HBsAg,了解HAV和HBV的流行状况。结果居民中抗-HAV IgG阳性率为63.08%,低于全国平均水平,HBsAg阳性率为12.80%。11~20岁青少年抗HAV-IgG阳性率为83.33%,61岁~老年人阳性率为9.09%,明显低于其他人群(P<0.05)。61岁~老年人中HBsAg阳性率为24.24%,明显高于41~60岁人群(10.07%和7.37%)(P<0.05)。结论甘肃省武威市农村地区青少年HAV感染率高,61岁~居民对HAV的特异性免疫力低。人群中HBV感染率高。应进一步加强病毒性肝炎的健康教育和甲、乙型肝炎疫苗的预防接种工作。
Objective To investigate the prevalence of hepatitis A virus (HAV) and hepatitis B virus (HBV) among rural residents in Wuwei City, Gansu Province. Methods A total of 539 people from 4 townships were surveyed by random sampling method. Serum anti-HAV IgG and HBsAg were detected by ELISA, and the prevalence of HAV and HBV was determined. Results The positive rate of anti-HAV IgG among residents was 63.08%, lower than the national average level, and the positive rate of HBsAg was 12.80%. The positive rate of anti-HAV-IgG in adolescents aged 11-20 years was 83.33%, and the positive rate in 61-year-olds was 9.09%, which was significantly lower than other groups (P <0.05). The positive rate of HBsAg in 61-year-old to elderly was 24.24%, which was significantly higher than that in 41-60 years old (10.07% and 7.37%) (P <0.05). Conclusion The incidence of HAV infection among rural adolescents in Wuwei City, Gansu Province is high, and the specific immunity against HAV of 61-year-old residents is low. HBV infection rate in the crowd is high. Should further strengthen the health education of viral hepatitis and hepatitis A, hepatitis B vaccine vaccination.