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目的 研究复方苏木煎剂对荷肝癌小鼠细胞外液蛋白含量的影响及作用。方法 收集实验中各组动物胸腺、脾、肿瘤组织细胞外液,检测其蛋白含量及其对肿瘤干细胞克隆形成的影响。结果 中药治疗组细胞外液蛋白含量较荷瘤组高,并对肿瘤干细胞克隆形成有明显抑制作用。结论 复方苏木煎剂可以提高荷瘤小鼠胸腺、脾细胞外液蛋白含量,此蛋白的某些组分对肿瘤细胞具有抑制活性。
Objective To study the effect of compound Sumu decoction on extracellular fluid protein content in hepatoma-bearing mice. Methods The extracellular fluids of thymus, spleen and tumor tissues in each group were collected to detect the protein content and its effect on the formation of tumor stem cells. Results The content of extracellular fluid protein in Chinese medicine treatment group was higher than that in tumor-bearing group, and it significantly inhibited the formation of tumor stem cell clones. Conclusion Compound Hemu Decoction can increase the protein content of thymus and spleen extracellular fluid in tumor-bearing mice. Some components of this protein have inhibitory activity on tumor cells.