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ｐ73基因是新发现的基因 ,与结肠癌的关系尚不清楚。我们通过检测 ｐ73在结肠癌及结肠腺瘤中的表达情况 ,并检测其所在基因位点的突变、缺失情况 ,以期探讨其在结肠癌发生、发展中的作用。材料和方法一、材料结肠癌 40例、结肠腺瘤 49例及正常组织 12例的标本 ,均取自 1999年 3
The p73 gene is a newly discovered gene, and the relationship with colon cancer is not clear. We examined the expression of p73 in colon cancer and colon adenomas, and detected mutations and deletions of the gene locus in order to explore its role in the occurrence and development of colon cancer. Materials and Methods 1. Materials 40 cases of colon cancer, 49 cases of colon adenoma and 12 cases of normal tissue were taken from 1999. 3