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目的探讨内镜下硬化剂注射治疗食管静脉曲张破裂出血的疗效。方法食管静脉曲张破裂出血患者157例,24h内行内镜下注射5%鱼肝油酸钠或1%聚桂醇治疗。观察治疗结果及并发症发生情况。结果 157例中,1次治疗出血停止者150例(95.5%),其中包括术中出血采用镜身压迫破口以及局部注射少量组织胶后出血停止者。7例未能止血者中,6例行三腔二囊管压迫止血,短期内未再出血;1例止血失败死亡。出现的并发症包括术中短暂出血42例(26.8%)、胸痛30例(19.1%)、低热20例(12.7%)、注射点糜烂或溃疡9例(5.7%)和食管穿孔1例(0.6%)。结论内镜下硬化剂注射治疗食管静脉曲张破裂出血疗效好,操作简便和安全。
Objective To investigate the efficacy of endoscopic sclerotherapy for esophageal variceal bleeding. Methods 157 cases of esophageal variceal bleeding in patients underwent endoscopic injection of 5% sodium morrhuate or 1% lauromacrogol treatment. Observe the treatment results and complications. Results Among the 157 cases, 150 cases (95.5%) of the bleeding stopped in one time, including intraoperative bleeding with lens compression and local bleeding with a small amount of tissue glue stop bleeding. Of the 7 patients who failed to stop the bleeding, 6 patients underwent three-chamber two-capsule compression and stopped bleeding within a short period of time. One patient died of hemostasis failure. Complications included 42 cases (26.8%) of intraoperative hemorrhage, 30 cases (19.1%) of chest pain, 20 cases (12.7%) of low fever, 9 cases (5.7%) of erosion or ulcer at injection site and 1 case %). Conclusion Endoscopic sclerotherapy for esophageal variceal bleeding is effective, safe and easy to operate.