目的通过对颈动脉内中膜厚度(intima-media thickness,IMT)及斑块检出,探讨颈动脉硬化与冠心病(CHD)的相关性。方法应用彩色多普勒超声成像仪对149例疑似冠心病者测定IMT及对斑块分级,并通过冠状动脉造影(CAG)检查分为冠心病组99例和非冠心病组50例,比较两组间颈动脉IMT、斑块指数及颈动脉斑块检出率。结果冠心病组颈动脉IMT(t=2.578)、斑块指数(t=3.182)显著高于非冠心病组(P<0.01);冠心病组颈动脉粥样硬化斑块检出率较非冠心病组明显增高。结论颈动脉粥样硬化斑块与冠心病密切相关,是及早预测冠心病的一个较好指标。 Objective To explore the correlation between carotid atherosclerosis and coronary heart disease (CHD) by detecting carotid intima-media thickness (IMT) and plaques. Methods Fifty-nine patients with suspected coronary heart disease were enrolled in this study. IMT and plaque grade were assessed by coronary angiography (CAG) and divided into coronary heart disease group (99 cases) and non-coronary heart disease group (50 cases) Carotid IMT, plaque index and carotid plaque detection rate among groups. Results The carotid IMT (t = 2.578) and plaque index (t = 3.182) in CHD group were significantly higher than those in non-CHD group (P <0.01). The prevalence of carotid atherosclerosis in CHD group was significantly lower than that in non-CHD group Heart disease group was significantly higher. Conclusions Carotid atherosclerotic plaque is closely related to coronary heart disease, which is a good indicator of early prediction of coronary heart disease.